Relative cortico-subcortical shift in brain activity but preserved training-induced neural modulation in older adults during bimanual motor learning


To study age-related differences in neural activation during motor learning, functional magnetic resonance imaging (fMRI) scans were acquired from 25 young (mean 21.5 years old) and 18 older adults (mean 68.6 years old) while performing a bimanual coordination task before (pre-test) and after (post-test) a 2-week training intervention on the task. We studied whether task-related brain activity and training-induced brain activation changes differed between age groups, particularly with respect to the hyperactivation typically observed in older adults.📍

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